{"id":12687,"date":"2026-03-22T09:21:00","date_gmt":"2026-03-22T09:21:00","guid":{"rendered":"https:\/\/www.kkltrust.org\/?p=12687"},"modified":"2026-03-24T12:04:39","modified_gmt":"2026-03-24T12:04:39","slug":"researchers-unveil-a-breakthrough-targeted-therapy-for-a-rare-blood-cancer","status":"publish","type":"post","link":"https:\/\/www.kkltrust.org\/?p=12687","title":{"rendered":"Researchers unveil a breakthrough targeted therapy for a rare blood cancer"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"12687\" class=\"elementor elementor-12687\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6235eaf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6235eaf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8f95157\" data-id=\"8f95157\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-42f0101 elementor-widget elementor-widget-text-editor\" data-id=\"42f0101\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"206\" data-end=\"492\">Researchers have developed a <em data-start=\"235\" data-end=\"253\">targeted therapy<\/em> offering new hope for patients living with a rare form of blood cancer. By focusing on specific cancer cells while sparing healthy ones, this innovation represents a significant step toward more effective and less toxic treatment options.<\/p><p class=\"continue-read-break\" data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">\u201cPeople with myelofibrosis are often treated with therapies that help control symptoms, but they don&#8217;t selectively target the abnormal cells driving the disease,\u201d said Prof Daniel Thomas, director of the South Australian Health and Medical Research Institute&#8217;s (SAHMRI) Blood Cancer programme.<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">\u201cOur research shows that by focusing on what makes these cells different, it may be possible to develop treatments that are both more effective and more targeted. This is part of a major paradigm shift in the treatment of myelofibrosis and related diseases,\u201d Thomas added.<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">Using the patient cells, the team found two different targets that optimally remove the culprit cells.<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">The study highlights the potential of precision immunology, an approach that uses the immune system to recognise and act on disease-causing cells while leaving healthy cells largely unaffected.<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">The findings suggest that different biological forms of the disease may benefit from different targeted strategies.<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">\u201cThe future of cancer treatment lies in understanding disease at a molecular and immune level and then translating that knowledge into therapies that are, potent, long-lasting and precise,\u201d Angel Lopez, Head of Human Immunology at SA Pathology,<\/p><p data-t=\"{&quot;n&quot;:&quot;blueLinks&quot;,&quot;t&quot;:13,&quot;a&quot;:&quot;click&quot;,&quot;b&quot;:76}\">While the findings are promising, further research and clinical development are needed before the approach can be tested in patients.<\/p><p data-start=\"494\" data-end=\"727\">At KKLT, we know that every breakthrough brings us closer to a future where blood cancer is no longer a life-threatening diagnosis. But progress like this is only possible through continued research, awareness, and community support.<\/p><p data-start=\"729\" data-end=\"928\"><strong data-start=\"732\" data-end=\"752\">What this means:<\/strong><br \/>\u2022 More precise and personalised treatment options<br data-start=\"802\" data-end=\"805\" \/>\u2022 Reduced side effects compared to traditional therapies<br data-start=\"861\" data-end=\"864\" \/>\u2022 Renewed hope for patients and families facing rare diagnoses<\/p><p data-start=\"930\" data-end=\"1120\"><strong data-start=\"933\" data-end=\"952\">Why it matters:<\/strong><br \/>Many rare blood cancers still lack effective treatments. Advancements like this highlight the critical need to invest in research and expand access to innovative care.<\/p><p data-start=\"1122\" data-end=\"1234\"><strong data-start=\"1125\" data-end=\"1150\">Be part of the change<\/strong><br \/>Support life-saving research. Raise awareness. Help us reach more patients in need.<\/p><p data-start=\"1236\" data-end=\"1294\">Together, we can turn breakthroughs into survival stories.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Researchers have developed a targeted therapy offering new hope for patients living with a rare form of blood cancer. By focusing on specific cancer cells while sparing healthy ones, this innovation represents a significant step toward more effective and less toxic treatment options. \u201cPeople with myelofibrosis are often treated with [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":12690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_theme","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-12687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v18.3 (Yoast SEO v27.1.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Researchers unveil a breakthrough targeted therapy for a rare blood cancer - Kevin Kararwa Leukaemia Trust<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kkltrust.org\/?p=12687\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Researchers unveil a breakthrough targeted therapy for a rare blood cancer\" \/>\n<meta property=\"og:description\" content=\"Researchers have developed a targeted therapy offering new hope for patients living with a rare form of blood cancer. By focusing on specific cancer cells while sparing healthy ones, this innovation represents a significant step toward more effective and less toxic treatment options. \u201cPeople with myelofibrosis are often treated with [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kkltrust.org\/?p=12687\" \/>\n<meta property=\"og:site_name\" content=\"Kevin Kararwa Leukaemia Trust\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/KKLTrust\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-22T09:21:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-24T12:04:39+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kkltrust.org\/wp-content\/uploads\/2026\/03\/Targeted-Therapy-For-Rare-Blood-Cancer-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"853\" \/>\n\t<meta property=\"og:image:height\" content=\"442\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kklttrust\" \/>\n<meta name=\"twitter:site\" content=\"@kklttrust\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.kkltrust.org\/?p=12687#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.kkltrust.org\/?p=12687\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/www.kkltrust.org\/#\/schema\/person\/881d2712886b696377e9b55d6f8c4995\"},\"headline\":\"Researchers unveil a breakthrough targeted therapy for a rare blood cancer\",\"datePublished\":\"2026-03-22T09:21:00+00:00\",\"dateModified\":\"2026-03-24T12:04:39+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.kkltrust.org\/?p=12687\"},\"wordCount\":373,\"publisher\":{\"@id\":\"https:\/\/www.kkltrust.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.kkltrust.org\/?p=12687#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kkltrust.org\/wp-content\/uploads\/2026\/03\/Targeted-Therapy-For-Rare-Blood-Cancer-1.jpg\",\"articleSection\":[\"news\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.kkltrust.org\/?p=12687\",\"url\":\"https:\/\/www.kkltrust.org\/?p=12687\",\"name\":\"Researchers unveil a breakthrough targeted therapy for a rare blood cancer - 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