The NHS is urging the public to pay attention to changes in their health this winter — particularly if you notice you’re looking unusually pale or feeling more tired than usual. While these signs can be caused by many common conditions, they can also be early indicators of acute myeloid leukaemia (AML), a fast-developing type of blood cancer that requires urgent treatment.
AML is rare, with around 3,100 new cases diagnosed each year in the UK, and it mainly affects older adults, especially those over 75. It develops in specific myeloid white blood cells — including monocytes and granulocytes — which normally protect the body from infection.
Key symptoms to look out for
Symptoms often come on over a few weeks and worsen with time. Speak to your GP if you notice:
Unusual or persistent paleness
Feeling weak, exhausted, or short of breath
Frequent infections
Unexplained bruising or bleeding (nosebleeds, bleeding gums)
Weight loss you can’t explain
Night sweats
The NHS stresses that in most cases, these symptoms will not be caused by leukaemia but they should be checked. Early consultation often means fewer tests and faster answers.
Diagnosis and next steps
If your GP suspects a problem after routine blood tests, you’ll be urgently referred to a haematologist for specialist investigations and, if needed, treatment. Acting quickly gives people the best chance of receiving timely care.
If you or your child notice any of these symptoms, don’t wait, contact your GP. Early action can make all the difference.


